Nicotinamide mononucleotide (NMN) supplements have recently gained popularity due to their potential health benefits. NMN is a naturally occurring molecule and a popular dietary supplement marketed as a NAD+ booster. Oral administration of nicotinamide mononucleotide is safe and effective in increasing blood nicotinamide adenine dinucleotide levels in healthy subjects. Studies have found that oral administration of nicotinamide mononucleotide can improve clinical parameters and nicotinamide metabolite levels in healthy individuals, making it a promising supplement for those looking to improve their overall health and wellness.

NMN supplementation has been a research topic for its effects on human health. However, limited information about its effects on humans is available as clinical trials are still in their early stages. In a study of middle-aged healthy adults, NMN supplementation improved physical performance as measured by a six-minute walking test in the 300 mg, 600 mg, and 900 mg groups. Additionally, supplementation with NMN has been shown to positively affect lysosomal function and autophagy in mice models, reducing heart failure and extending lifespan. Further research is needed to understand the effects of NMN supplementation on human health fully.

NMN supplements have gained popularity among people looking for the fountain of youth. It is believed that they can help reverse the effects of aging and improve metabolism in humans. Despite lacking strong human evidence, some experts believe in its anti-aging and health-enhancing benefits. However, the high cost of these supplements may be a barrier to some people seeking their benefits. Researchers are still studying NMN in humans to determine its safety risks and most effective dosage at room temperature.

NMN supplements have been shown to affect overall health and aging positively. Studies on mice and rats have shown positive effects on metabolism, liver, skin, muscle, and brain function and improved bone structure, vascular health, reproduction, immune system function, and lifespan. Human studies, particularly on postmenopausal women, are still in their early days, but initial data is promising. NMN may also increase NAD+ synthesis, which helps counteract age-related decline and reduces the risk of age-related diseases such as type 2 diabetes and Alzheimer’s disease. Furthermore, a 2019 study revealed positive effects on older adults’ NAD+ levels after 12 weeks of aerobic and resistance exercise. The effects of NMN supplementation, particularly on postmenopausal women, show potential for improving metabolic health and overall well-being.