Harvard Study Reveals NMN Reduces Weight, Cholesterol, and Blood Pressure in Overweight Adults

Harvard Study Reveals NMN Reduces Weight, Cholesterol, and Blood Pressure in Overweight Adults

In a groundbreaking study, Harvard researchers have unveiled promising findings about Nicotinamide Mononucleotide (NMN), a compound that could revolutionize the management of weight, cholesterol, and blood pressure in overweight adults. Here at Ensonkan, we are dedicated to bringing you the latest in health and wellness research, and this new study is no exception.

What is NMN?

Nicotinamide Mononucleotide (NMN) is a naturally occurring molecule in all life forms. It is a precursor to Nicotinamide Adenine Dinucleotide (NAD+), a critical coenzyme in cellular metabolism and energy production. As we age, NAD+ levels in our bodies decline, leading to various health issues, including metabolic disorders, cardiovascular diseases, and obesity.

The Harvard Study

The study, conducted by a team of researchers at Harvard Medical School, involved a randomized, double-blind, placebo-controlled trial with overweight adults. Participants were given NMN supplements over a period of 12 weeks, and their weight, cholesterol levels, and blood pressure were monitored.

Key Findings:

Weight Reduction: Participants who took NMN supplements experienced a significant reduction in body weight compared to those who took a placebo. The average weight loss in the NMN group was 5% of their total body weight.

Cholesterol Levels: NMN supplementation led to a substantial decrease in total cholesterol and LDL ("bad") cholesterol levels, while HDL ("good") cholesterol levels remained stable. This finding is particularly important as high cholesterol is a major risk factor for cardiovascular diseases.

Blood Pressure: The study also reported a marked improvement in blood pressure readings among the NMN group. Both systolic and diastolic blood pressure levels showed a significant decrease, reducing the risk of hypertension-related complications.

How Does NMN Work?

NMN boosts NAD+ levels in the body, enhancing mitochondrial function and promoting cellular energy production. This process helps to improve metabolic rate, reduce fat accumulation, and support cardiovascular health. Additionally, NMN has been shown to activate sirtuins, proteins that play a crucial role in regulating inflammation, stress resistance, and aging.

Implications for Overweight Adults

The results of this study are particularly encouraging for overweight adults struggling with metabolic health issues. By incorporating NMN supplements into their daily routine, they can potentially achieve significant improvements in weight management, cholesterol levels, and blood pressure.

Safety and Dosage

While the study indicates promising results, it is important to consult with a healthcare provider before starting any new supplement regimen. The optimal dosage of NMN can vary based on individual health conditions and needs.


The Harvard study on NMN presents a new horizon for metabolic health management. At Ensonkan, we are committed to providing our readers with the latest advancements in health research. Stay tuned for more updates on NMN and other groundbreaking health discoveries.

NMN supplements at Ensonkan

Made with the highest quality ingredients, our supplements are pure vegetarian, contain no artificial colors, preservatives, or additives, and are gluten-free, NON-GMO, and suitable for vegans.

Ensonkan NMN + PQQ + PterostilbeneThis premium formula contains 250 mg of NMN (Nicotinamide Mononucleotide) and PQQ
(Pyrroloquinoline Quinone) 
for cellular energy and mitochondrial support. However, it includes an additional ingredient—Pterostilbene. Pterostilbene is a compound found in certain fruits, particularly in blueberries and grapes, known for its potent antioxidant and anti-inflammatory properties. By including Pterostilbene, this product aims to enhance the antioxidant benefits beyond the NMN and PQQ combination.

Ensonkan's NMN + PQQ : This classic formula contains 200 mg of NMN (Nicotinamide Mononucleotide) paired with PQQ (Pyrroloquinoline Quinone). NMN is a precursor to NAD+ (Nicotinamide Adenine Dinucleotide), crucial for cellular energy production and repair. PQQ complements NMN by supporting mitochondrial health and biogenesis, aiding in energy production within the cells.

For more information and to explore our range of health products, visit www.ensonkan.ca.

By integrating NMN into your wellness routine, you may be taking a significant step toward a healthier, more vibrant life. Keep following Ensonkan for the latest insights and tips on achieving optimal health and wellness.



Pencina KM, Valderrabano R, Wipper B, Orkaby AR, Reid KF, Storer T, Lin AP, Merugumala S, Wilson L, Latham N, Ghattas-Puylara C, Ozimek NE, Cheng M, Bhargava A, Memish-Beleva Y, Lawney B, Lavu S, Swain PM, Apte RS, Sinclair DA, Livingston D, Bhasin S. Nicotinamide Adenine Dinucleotide Augmentation in Overweight or Obese Middle-Aged and Older Adults: A Physiologic Study. J Clin Endocrinol Metab. 2023 Feb 6. doi: 10.1210/clinem/dgad027. Epub ahead of print. PMID: 36740954